Публикации

Лаборатория протеомики

  • Основы персонифицированной наномедицины: наноматериалы в биологии и медицине

2016 - 2018 гг. - исследования по международному гранту No. 19806/2016 “INNOVIMMUNE: Baltic Platform for Innovative Immunotherapies” c Каролинска университетом (Швеция), Рижским университетом (Латвия), Медуниверситетом им Пирогова (Россия).

КНИГИ:

1. D. Shcharbin, B. Klajnert, M. Bryszewska. Practical Guide to Studying Dendrimers. Book, iSmithers Rapra Publishing: Shawbury, Shrewsbury, Shropshire, UK, 2010. 120 p. ISBN: 978-1-84735-444-0.

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СТАТЬИ:

2018

1. Shcharbin D., N. Shcharbina, E. Pedziwiatr-Werbicka, J. de la Mata,R. Gomez-Ramirez, S. Mignani, V. A. Kulchitsky, M.-A. Muñoz-Fernández, A.-M. Caminade, J.-P. Majoral, and M. Bryszewska (2018). Phosphorus Dendrimers as Vectors for Gene Therapy in Cancer // pp. 227-244, chapter 8 in book “Phosphorous Dendrimers in Biology and Nanomedicine: Syntheses, Characterization, and Properties” (Edited by A.-M. Caminade, J.-P. Majoral, and C.-O. Turrin), 2018, Pan Stanford Publishing Pte Ltd., Singapore, ISBN 978-981-4774-33-8, 400 p.

2. Ihnatsyeu-Kachan A., V. Dzmitruk, E. Apartsin, O. Krasheninina, M. Ionov, S. Loznikova, A. Venyaminova, K. Milowska, D. Shcharbin, S. Mignani, M.-A. Muñoz-Fernández, J.-P. Majoral, M. Bryszewska. Multi-target inhibition of cancer cell growth by siRNA cocktails and 5-fluorouracil using effective piperidine-terminated phosphorus dendrimers // Colloids and Interfaces. 2018. Vol. 1 (1). N 6.  OPEN ACCESS:  http://www.mdpi.com/2504-5377/1/1/6

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2017

1. Shcharbin D., E. Pedziwiatr-Werbicka, A. Vcherashniaya, A. Janaszewska, M. Marcinkowska, P. Goska, B. Klajnert-Maculewicz, M. Ionov, V. Abashkin, A. Ihnatsyeu-Kachan, J. de la Mata, P. Ortega, R. Gomez-Ramirez, J.-P. Majoral, M. Bryszewska. Binding of poly(amidoamine), carbosilane, phosphorus and hybrid dendrimers to thrombin - constants and mechanisms // Colloids and Surfaces B. 2017. Vol. 155. P. 11-16. Impact Factor = 3.902.

2. Shcharbin D., N. Shcharbina, V. Dzmitruk, E. Pedziwiatr-Werbicka, M. Ionov, S. Mignani, F. J. de la Mata, R. Gómez, M. A. Muñoz-Fernández, J.-P. Majoral, M. Bryszewska. Dendrimer-Protein Interactions versus Dendrimer-Based Nanomedicine // Colloids and Surfaces B. 2017. Vol. 152. P. 414-422. Impact Factor = 3.902.

3. Peña-González C., Pedziwiatr-Werbicka E, Shcharbin D, Guerrero-Beltrán C, Abashkin V, Loznikova S, Jimenez JL, Muñoz-Fernádez M.Á, Bryszewska M, Gomez Ramirez R, Sánchez-Nieves J, de la Mata J. Gold Nanoparticles Stabilized by Cationic Carbosilane Dendrons: Synthesis, Characterization and Biological Properties // Dalton Transactions. 2017. Vol. 46. P. 8736-8745. Impact Factor = 4.177.

4. Michlewska S, Ionov M, Shcharbin D, Maroto-Díaz M, Gomez Ramirez R, de la Mata FJ, Bryszewska M. Ruthenium metallodendrimers with anticancer potential in an acute promyelocytic leukemia cell line (HL60) // European Polymer Journal. 2017. Vol. 87. P. 39-47. Impact Factor = 3.485.

5. Mignani S., M. Bryszewska, M. Zablocka, B. Klajnert-Maculewicz, J. Cladera, D. Shcharbin, J.-P. Majoral. Can dendrimer-based nanoparticles fight neurodegenerative diseases? Current situation versus other established approaches // Progress in Polymer Science. 2017. Vol. 64. P. 23-51. Impact Factor = 27.184.

6. Pedziwiatr-Werbicka E., Serchenya T., Shcharbin D., Terekhova M., Prokhira E., Shyrochyna I., Sviridov O., Peña-González C.E., Gómez R., Sánchez-Nieves J., de la Mata F.J., Bryszewska M. Dendronization of Gold Nanoparticles Decreases Their Impact on Human Alpha-1-Microglobulin // International Journal of Biological Macromolecules. Just Accepted. DOI: 10.1016/j.ijbiomac.2017.11.004. 5-Years Impact Factor = 3.657.

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2016

1. M. Ionov, A. Ihnatsyeu-Kachan, S. Michlewska, N. Shcharbina, D. Shcharbin, J.-P. Majoral, M. Bryszewska. Effect of dendrimers on selected enzymes - evaluation of nano carriers // International Journal of Pharmaceutics. 2016. V. 499. P. 247-254. Impact Factor 2015 = 3.994. http://www.sciencedirect.com/science/article/pii/S0378517315304579

2.  A. Szwed, K. Milowska, M. Ionov, D. Shcharbin, S. Moreno, R. Gomez Ramirez, J. de la Mata, J.-P. Majoral, M. Bryszewska, T. Gabryelak. Interaction between dendrimers and regulatory proteins. Comparison of effects of carbosilane and carbosilane-viologen-phosphorus dendrimers // RSC Advances. 2016. Vol. 6. P. 97546-97554. Impact Factor 2015 = 3.289. http://pubs.rsc.org/en/content/articlelanding/2016/ra/c6ra16558c

2015

1. V. Dzmitruk, A. Szulc, D. Shcharbin, A. Janaszewska, N. Shcharbina, J. Lazniewska, D. Novopashina, M. Buyanova, M. Ionov, B. Klajnert-Maculewicz, R. Gómez-Ramirez, S. Mignani, J.-P. Majoral, M.A. Muñoz-Fernández, M. Bryszewska. Anticancer siRNA cocktails as a novel tool to treat cancer cells. Part (B). Efficiency of therapeutic action // International Journal of Pharmaceutics. 2015. Vol. 485. P. 288-294. Impact Factor 2013 = 3.785. http://www.sciencedirect.com/science/article/pii/S0378517315002501

2. M. Ionov, J. Lazniewska, V. Dzmitruk, I. Halets, S. Loznikova, D. Novopashina, E. Apartsin, O. Krasheninina, A. Venyaminova, K. Milowska, O. Nowacka, R. Gomez-Ramirez, F. J. de la Mata, J.-P. Majoral, D. Shcharbin, M. Bryszewska. Anticancer siRNA cocktails as a novel tool to treat cancer cells. Part (A). Mechanisms of interaction // International Journal of Pharmaceutics. 2015. Vol. 485. P. 261-269. Impact Factor 2013 = 3.785. http://www.sciencedirect.com/science/article/pii/S0378517315002409

3. M. Ionov, K. Ciepluch, Z. Garaiova, S. Melikishvili, S. Michlewska, Ł. Balcerzak, S. Glińska, K. Miłowska, R. Gomez Ramirez, F. J. de la Mata, D. Shcharbin, I. Waczulikova, M. Bryszewska, T. Hianik. Dendrimers complexed with HIV-1 peptides interact with liposomes and lipid monolayers // BBA - Biomembranes. 2015. Vol. 1848. P. 907-915. - Impact Factor 2013 = 3.431. http://www.sciencedirect.com/science/article/pii/S0005273615000036

4. D. Shcharbin, N. Shcharbina, A. Shakhbazau, S. Mignani, J.-P. Majoral, M. Bryszewska, Phosphorus-Containing Nanoparticles: Biomedical Patents Review // Expert Opinion on Therapeutic Patents. 2015. Vol. 25. P. 539-548.  Impact Factor 2013 = 3.441. http://informahealthcare.com/doi/abs/10.1517/13543776.2015.1010512

5. Shcharbin D., M. Ionov, V. Abashkin, S. Loznikova, V. Dzmitruk, N. Shcharbina, L. Matusevich, K. Milowska, K. Gałęcki, S. Wysocki, M. Bryszewska. Nanoparticle Corona for Proteins: Mechanisms of Interaction between Dendrimers and Proteins // Colloids and Surfaces B: Biointerfaces. 2015. Vol. 134. P. 377-383. Impact Factor 2014 = 4.152. http://www.sciencedirect.com/science/article/pii/S0927776515300515

6. Shakhbazau A, Mishra M, Chu TH, Brideau C, Cummins K, Tsutsui S, Shcharbin D, Majoral JP, Mignani S, Blanchard-Desce M, Bryszewska M, Wee Yong V, Stys PK, van Minnen J. Fluorescent phosphorus dendrimer as a spectral nanosensor for macrophage polarization and fate tracking in spinal cord injury. // Macromolecular Bioscience. 2015. DOI: 10.1002/mabi.201500150. Impact Factor 2014 = 3.650. http://onlinelibrary.wiley.com/doi/10.1002/mabi.201500150/abstract

6. Shakhbazau A, Mishra M, Chu TH, Brideau C, Cummins K, Tsutsui S, Shcharbin D, Majoral JP, Mignani S, Blanchard-Desce M, Bryszewska M, Wee Yong V, Stys PK, van Minnen J. Fluorescent phosphorus dendrimer as a spectral nanosensor for macrophage polarization and fate tracking in spinal cord injury. // Macromolecular Bioscience. 2015. DOI: 10.1002/mabi.201500150. Impact Factor 2014 = 3.650. http://onlinelibrary.wiley.com/doi/10.1002/mabi.201500150/abstract

7. О.Г. Дмитрук, Э. Вербицка-Пендзивятр, Д. Г. Щербин, Р. Гомез, Ф.-Х. де ла Мата, Ж.-П. Мажораль, C. Миньяни, М. Брышевска. Агрегация тромбоцитов в присутствии катионных дендримеров и их комплексов с миРНК и ОДН и влияние альбуминов на данный процесс // Новости медико-биологических наук. – 2015. – Т.12. - №4. – С.139-143

2014

1. O. Nowacka, D. Shcharbin, B. Klajnert-Maculewicz, M. Bryszewska, Stabilizing effect of small concentrations of PAMAM dendrimers at the insulin aggregation // Colloids and Surfaces B: Biointerfaces. 2014. Vol. 116. P. 757-760. Impact Factor 2013 = 4.287. http://www.sciencedirect.com/science/article/pii/S0927776514000708

2. Vladimir I. Potkin, Dzmitry Shcharbin, Andrew A. Denisov, Svetlana G. Paschkevich, Maria Bryszewska, Sergey K. Petkevich, Alexey V. Kletskov, Dmitri O. Lapotko, Vladimir V. Kazbanov, Tatiana A. Gurinovich, Vladimir A. Kulchitsky, The Influence of Heterocyclic Compounds with PAMAM Dendrimers Complexes on Evoked Electrical Responses in Brain Slices in Hypoxia // Cellular & Molecular Biology Letters. 2014. Vol. 19. P. 243-248. Impact Factor 2013 = 1.782. http://link.springer.com/article/10.2478/s11658-014-0193-5

3. D. Shcharbin, A. Janaszewska, B. Klajnert-Maculewicz, B. Ziemba, V. Dzmitruk, I. Halets, S. Loznikova, N. Shcharbina, K. Milowska, M. Ionov, A. Shakhbazau, M. Bryszewska. How to study Dendrimers and Dendriplexes III. Biodistribution, Pharmacokinetics and Toxicity In vivo // Journal of Controlled Release. 2014. Vol.181. P. 40-52. Impact Factor 2013 = 7.261. http://www.sciencedirect.com/science/article/pii/S0168365914001217

4. A. Shakhbazau, S.J. Archibald, D. Shcharbin, M. Bryszewska, R. Midha. Aligned collagen-GAG matrix as a 3D substrate for Schwann cell migration and dendrimer-based gene delivery // Journal of Materials Science: Materials in Medicine. 2014. Vol. 25. P. 1979-1989. Impact factor 2013 = 2.378. http://link.springer.com/article/10.1007/s10856-014-5224-2

5. D. Shcharbin, N. Shcharbina, M. Bryszewska. Recent patents in dendrimers for nanomedicine: evolution 2014 // Recent Patents on Nanomedicine. 2014. Vol. 4. P. 25-31. Open Access Article. http://benthamscience.com/journal/abstracts.php?journalID=rpnanom&articleID=122668

6. D. Shcharbin, N. Shcharbina, K. Milowska, F. J. de la Mata, M. A. Munoz-Fernandez, S. Mignani, R. Gomez-Ramirez, J.-P. Majoral, M. Bryszewska. Interference of cationic polymeric nanoparticles with clinical chemistry tests - clinical relevance // International Journal of Pharmaceutics. 2014. V. 473. P. 599-606. Impact Factor 2013 = 3.785. http://www.sciencedirect.com/science/article/pii/S0378517314005535

7. C.Ж. Лозникова, А.А. Cуxодола, Н.Ю. Шчаpбина, Д.Г. Шчаpбин. Влияние магния, ацетилcалициловой киcлоты и эмокcипина на агpегацию тpомбоцитов. Биофизика, 2014, том 59, вып. 6, c. 1108–1112.

8. И. В. Галец-Буй, А. А. Суходола, Д. Г. Щербин. Подвижность хромофоров, поглощающих свет в диапазоне 320-420 нм, в ткани прозрачных и катарактальных хрусталиков. ЖПС. 2014. Т. 81 (5). С. 747-753.

2013

1. E. Pedziwiatr-Werbicka, E. Fuentes, V. Dzmitruk, J. Sánchez-Nieves, M. Sudas, E. Drozd, A. Shakhbazau, D. Shcharbin, F.J. de la Mata, R. Gomez-Ramirez, M.A. Munoz-Fernandez, M. Bryszewska. Novel ‘Si-C’ carbosilane dendrimers as carriers for anti-HIV nucleic acids: studies on complexation and interaction with blood cells // Colloids and Surfaces B: Biointerfaces. 2013. Vol. 109, P. 183-189. Impact Factor 2012 = 3.554. http://www.sciencedirect.com/science/article/pii/S0927776513002324

2. N. Shcharbina, D. Shcharbin, M. Bryszewska. Nanomaterials in Stroke Treatment: Perspectives // Stroke. 2013. V. 44. P. 2351-2355. Impact Factor 2012 = 6.158. http://stroke.ahajournals.org/content/44/8/2351.full.pdf?ijkey=AhHgqn9h8pZWzca&keytype=ref

3. I. Halets, D. Shcharbin, B. Klajnert, M. Bryszewska. Contribution of hydrophobicity, DNA and proteins to the cytotoxicity of cationic PAMAM dendrimers // International Journal of Pharmaceutics. 2013. Vol. 454. P. 1-3. Impact factor 2012 = 3.458. http://www.sciencedirect.com/science/article/pii/S0378517313005814

4. A. Shakhbazau, C. Mohanty, D. Shcharbin, M. Bryszewska, A.M. Caminade, J.-P. Majoral, J. Alant, R. Midha. Doxycycline-regulated GDNF expression promotes axonal regeneration and functional recovery in transected peripheral nerve. // Journal of Controlled Release, 2013, V. 172, P. 841-851. Impact Factor 2012 = 7.633. http://dx.doi.org/10.1016/j.jconrel.2013.10.004.

5. D. Shcharbin, A. Shakhbazau, M. Bryszewska, Poly(amidoamine) dendrimer complexes as a platform for gene delivery // Expert Opinion on Drug Delivery, 2013, V. 10 (12), p. 1687-1698. Impact Factor 2012 = 4.869. http://informahealthcare.com/doi/abs/10.1517/17425247.2013.853661

2012

1. E. Pedziwiatr-Werbicka, D. Shcharbin, M. Bryszewska, J. Maly, M. Maly, M. Zaborski, B. Gabara, P. Ortega, F. J. de la Mata, R. Gómez, Mª A. Muñoz-Fernandez, Carbosilane dendrimers as a non-viral delivery system for antisense oligonucleotides-characterization of dendriplexes // Journal of Biomedical Nanotechnology, 2012, Vol. 8 (1), p. 57-73. Impact Factor 2011 = 4.216. http://www.aspbs.com/jbn.html.

2. A. Shakhbazau, D. Shcharbin, N. Petyovka, N. Goncharova, I. Seviaryn, S. Kosmacheva, M. Bryszewska, M. Potapnev, Non-virally modified human mesenchymal stem cells produce ciliary neurotrophic factor in biodegradable fibrin-based 3D scaffolds // Journal of Pharmaceutical Sciences, 2012, Vol. 101 (4), p. 1546-1554. Impact Factor 2011 = 3.055. http://onlinelibrary.wiley.com/doi/10.1002/jps.23033/abstract

3. С.Г. Пашкевич, А.А. Денисов, Р. Александрова, Д. Иванов, М. Александров, А.В. Клецков, Д.Г. Щербин, С.К. Петкевич, В.В. Казбанов, Б. Андорова-Лилова, В.И. Поткин, В.А. Кульчицкий. Сочетание дендримеров и гетероциклических соединений сопровождается ингибированием вызванных ответов в гиппокампе при гипоксии // Новости медико-биологических наук. 2012, Том 5, № 1, С. 28-31.

4. Barbara Ziemba, Inessa Halets, Dzmitry Shcharbin, Dietmar Appelhans, Brigitte Voit, Ireneusz Pieszynski, Maria Bryszewska, Barbara Klajnert, Influence of 4th generation poly(propyleneimine) dendrimers on blood cells // Journal of Biomedical Materials Research Part A. 2012, 100 (11), 2870-2880. Impact Factor 2011 = 2.625. http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.34222/abstract

5. Antos Shakhbazau, Dzmitry Shcharbin, Ihar Seviaryn, Natalya Goncharova, Svetlana Kosmacheva, Mihail Potapnev, Maria Bryszewska, Ranjan Kumar, Jeffrey Biernaskie, and Rajiv Midha, Dendrimer-driven neurotrophin expression differs in temporal patterns between rodent and human stem cells // Molecular Pharmaceutics, 2012, Vol. 9 (5), P.1521-1528. Impact Factor 2011 = 4.782. http://pubs.acs.org/doi/abs/10.1021/mp300041k

6. Michal Ciolkowski, Inessa Halets, Dzmitry Shcharbin, Dietmar Appelhans, Brigitte Voit, Barbara Klajnert, Maria Bryszewska, Impact of maltose modified poly(propylene imine) dendrimers on liver alcohol dehydrogenase (LADH) internal dynamics and structure // New Journal of Chemistry. 2012, Vol. 36 (10), P. 1992-1999. Impact Factor 2011 = 2.605. http://pubs.rsc.org/en/content/articlelanding/2012/NJ/C2NJ40406K

7. Antos Shakhbazau, Dzmitry Shcharbin, Maria Bryszewska, Jeffrey Biernaskie, Ranjan Kumar, Michael S. Kallos, Natalya Goncharova, Ihar Seviaryn, Svetlana Kosmacheva, Mihail Potapnev, and Rajiv Midha, Non-viral engineering of skin precursor-derived Schwann cells for enhanced NT-3 production in adherent and microcarrier culture // Current Medicinal Chemistry, 2012, Vol. 19 (32), P. 5572-5579. Impact Factor 2011 = 4.859. http://www.benthamdirect.org/pages/b_viewarticle.php?articleID=3182515

8. Michal Szewczyk, Joanna Drzewinska, Volha Dzmitruk, Dzmitry Shcharbin, Barbara Klajnert, Dietmar Appelhans, Maria Bryszewska, Stability of dendriplexes formed by anti-HIV genetic material and polypropylenimine dendrimers in presence of glucosaminoglycans // Journal of Physical Chemistry B. 2012, 116 (50), pp 14525-14532. Impact Factor 2011 = 3.696. http://pubs.acs.org/doi/abs/10.1021/jp304449v

2011

1. D. Shcharbin, V. Dzmitruk, A. Shakhbazau, N. Goncharova, I. Seviaryn, S. Kosmacheva, M. Potapnev, E. Pedziwiatr-Werbicka, M. Bryszewska, M. Talabaev, A. Chernov, V. Kulchitsky, A.-M. Caminade, J.-P. Majoral, Fourth generation phosphorus-containing dendrimers: prospective drug and gene delivery carrier // Pharmaceutics. 2011, 3 (3), 458-473. Open access article. http://www.mdpi.com/1999-4923/3/3/458/

2. A. V. Shakhbazau, D. G. Shcharbin, N. V. Goncharova, I. N. Seviaryn, S. M. Kosmacheva, N. A. Kartel, M. Bryszewska, J. P. Majoral, and M. P. Potapnev. Neurons and Stromal Stem Cells as Targets for Polycation-Mediated Transfection // Bulletin of Experimental Biology and Medicine. 2011, 151 (1), 126-129. Impact Factor = 0.27. http://www.springerlink.com/content/323516447366k450/

3. Dzmitry Shcharbin, Elzbieta Pedziwiatr, Olga Nowacka, Mayank Kumar, Marian Zaborski, Paula Ortega, F. Javier de la Mata, Rafael Gomez, Ma Angeles Munoz-Fernandez, Maria Bryszewska. Carbosilane dendrimers NN8 and NN16 form a stable complex with siGAG1 // Colloids and Surfaces B: Biointerfaces. 2011, 83 (2), 388-391. Impact Factor = 2.78. http://preview.ncbi.nlm.nih.gov/pubmed/21145713

2010

1. Dzmitry Shcharbin, Elzbieta Pedziwiatr, Janusz Blasiak, Maria Bryszewska, How to Study Dendriplexes II: transfection and cytotoxicity // Journal of Controlled Release. 2010, 141 (2), 110-127. Impact Factor = 7.16. http://preview.ncbi.nlm.nih.gov/pubmed/19815039

2. A. Shakhbazau, I. Isayenka, N. Kartel, N. Goncharova, I. Sevyaryn, S. Kosmacheva, M. Potapnev, D. Shcharbin, M. Bryszewska, Transfection efficiencies of PAMAM dendrimers correlate inversely with their hydrophobicity // International Journal of Pharmaceutics. 2010, 383 (1-2), p.228-235. Impact Factor = 3.61. http://preview.ncbi.nlm.nih.gov/pubmed/19770028

3. A. Shakhbazau, D. Shcharbin, I. Isayenka, N. Goncharova, I. Sevyaryn, S. Kosmacheva, M. Potapnev, M. Ionov, B. Gabara, M. Bryszewska, Use of polyamidoamine dendrimers to engineer BDNF-producing human mesenchymal stem cells // Molecular Biology Reports. 2010, 37 (4), p. 2003-2008. Impact Factor = 1.89. http://preview.ncbi.nlm.nih.gov/pubmed/19649724

4. Д.Г. Щербин, Б. Клайнерт, М. Брышевска. Дендримеры и их применение в биологии и медицине (обзор) // Весці НАН Беларусі, Сер. біял. навук. 2010, № 2, С. 109–120.

2009

1. D.G. Shcharbin, B. Klajnert, M. Bryszewska. Dendrimers in gene transfection. Biochemistry (Mosc). 2009, 74 (10), 1070-1079. Impact Factor = 1.4. http://www.springerlink.com/content/r04m4g705767107j/

2. Shcharbin D., E. Pedziwiatr, M. Bryszewska, How to Study Dendriplexes I: characterization (review) // Journal of Controlled Release. 2009, 135 (3), 186-197. Impact Factor = 7.16. http://preview.ncbi.nlm.nih.gov/pubmed/19331857

3. Sękowski S., A. Kaźmierczak, J. Mazur, M. Przybyszewska, M. Zaborski, D. Shcharbin, T. Gabryelak. The interaction between PAMAM G3.5 dendrimer, Cd2+, dendrimer-Cd2+ complexes and human serum albumin // Colloids and Surfaces B: Biointerfaces, 2009, 69 (1), 95-98. Impact Factor = 2.78. http://preview.ncbi.nlm.nih.gov/pubmed/19108997

4. Д.Г. Щербин. Применение дендримеров в генетической терапии // Наука и Инновации. 2009, № 10 (80), с. 34-37. Статья в свободном доступе: http://innosfera.org/node/561

5. Shcharbin D. G., Palecz B., Bryszewska M. The binding of hippuric acid to cationic PAMAM by dendrimers. Proceedings of the National Academy of Sciences of Belarus, (Vestsi Natsiyanalnai Akademii Navuk Belarusi), Number 3, 2009, p. 64--67. http://nasb.gov.by/eng/publications/vestib/vbi09_3.php

2008

1. Weber N., P. Ortega, M.I. Clemente, D. Shcharbin, M. Bryszewska, F. J. de la Mata, R. Gómez and M. A. Muñoz-Fernández. Characterization of carbosilane dendrimers as effective carriers of siRNA to HIV infected lymphocytes. // Journal of Controlled Release. 2008, 132 (1), p. 55-64. Impact Factor = 7.16. http://preview.ncbi.nlm.nih.gov/pubmed/18727943

2. Pedziwiatr E., D. Shcharbin, L. Chonco, P. Ortega, F. J. de la Mata, R. Gómez, B. Klajnert, M. Bryszewska, Mª A. Muñoz-Fernandez. Binding properties of water-soluble carbosilane dendrimers // Journal of Fluorescence. 2009, 19 (2), 267-275. Impact Factor = 1.97. http://preview.ncbi.nlm.nih.gov/pubmed/18758926

3. Shcharbin D., M. F. Ottaviani, M. Cangiotti, M. Przybyszewska, M. Zaborski, M. Bryszewska. Impact of PAMAM G2 and G6 dendrimers on bovine serum albumin (fatty acids free and loaded with different fatty acids) // Colloids and Surfaces B: Biointerfaces, 2008, 63 (1), 27-33. Impact Factor = 2.78. http://preview.ncbi.nlm.nih.gov/pubmed/18068340

2007

1. Shcharbin D., E. Pedziwiatr, L. Chonco, J.F. Bermejo-Martín, P. Ortega, F. J. de la Mata, R. Eritja, R. Gómez, B. Klajnert, M. Bryszewska, Mª A. Muñoz-Fernandez, Analysis of interaction between dendriplexes and bovine serum albumin // Biomacromolecules. 2007, 8 (7), 2059-2062. Impact Factor = 5.30. http://preview.ncbi.nlm.nih.gov/pubmed/17583948

2. Shcharbin D., M. Janicka, M. Wasiak, B. Palecz, M. Przybyszewska, M. Zaborski, M. Bryszewska, Serum albumins have five sites for binding of PAMAM dendrimers // Biochim. Biophys. Acta, Proteins and Proteomics, 2007, 1774, 946-951. Impact Factor = 2.77. http://preview.ncbi.nlm.nih.gov/pubmed/17560838

3. Chonco L., J.F. Bermejo-Martín, P. Ortega, D. Shcharbin, E. Pedziwiatr, B. Klajnert, F. J. de la Mata, R. Eritja, R. Gómez, M. Bryszewska, Mª A. Muñoz-Fernandez, Water soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from the binding to serum proteins. // Organic & Biomolecular Chemistry. 2007, 5 (12), 1886-1893. Impact Factor = 3.45. http://preview.ncbi.nlm.nih.gov/pubmed/17551637

4. Shcharbin D., J. Mazur, M. Szwedzka, M. Wasiak, B. Palecz, M. Przybyszewska, M. Zaborski, M. Bryszewska, Interaction between PAMAM 4.5 dendrimer, cadmium and bovine serum albumin: a study using equilibrium dialysis, isothermal titration calorimetry, zeta-potential and fluorescence. // Colloids and Surfaces B: Biointerfaces. 2007, 58, 286-289. Impact Factor = 2.78. http://preview.ncbi.nlm.nih.gov/pubmed/17532194

5. Jokiel M., D. Shcharbin, J. Janiszewska, Z. Urbanczyk-Lipkowska, M. Bryszewska. The interaction between polycationic poly-lysine dendrimers and charged and neutral fluorescent probes. // Journal of Fluorescence. 2007, 17 (1), 73-79. Impact Factor = 1.97. http://preview.ncbi.nlm.nih.gov/pubmed/17180467

6. Klajnert B., A. Pastucha, D. Shcharbin, M. Bryszewska. Binding properties of polyamidoamine pendrimers // Journal of Applied Polymer Science. 2007, 103 (3), 2036–2040. Impact Factor = 1.37. http://onlinelibrary.wiley.com/doi/10.1002/app.25279/abstract

7. Shcharbin D., M. Szwedzka, M. Bryszewska. Does fluorescence of ANS reflect its binding to PAMAM dendrimers? // Bioorganic Chemistry. 2007, 35 (2), 170-174. Impact Factor = 1.47. http://preview.ncbi.nlm.nih.gov/pubmed/17126376

2006

1. Gabellieri E., G.B. Strambini, D. Shcharbin, B. Klajnert, M. Bryszewska. Dendrimer-protein interactions studied by Trp room temperature phosphorescence // Biochim. Biophys. Acta. Proteins and Proteomics. 2006, 1764 (11), 1750-1756. Impact Factor = 2.77. http://preview.ncbi.nlm.nih.gov/pubmed/17055349

2. Shcharbin D., A. Drapeza, V. Loban, A. Lisichenok, M. Bryszewska. Breakdown of Bilayer Lipid Membranes by Dendrimers // Cellular and Molecular Biology Letters. 2006, 11 (2), 242 - 248. Impact Factor = 1.46. http://preview.ncbi.nlm.nih.gov/pubmed/16847568

3. Shcharbin D., M. Bryszewska. Complex formation between endogenous toxin bilirubin and polyamidoamine dendrimers. A spectroscopic study // Biochem. Biophys. Acta. General Subjects. 2006, 1760 (7), 1021-1026. Impact Factor = 4.66. http://preview.ncbi.nlm.nih.gov/pubmed/16716522

4. Klajnert B., J. Janiszewska, Z. Urbanczyk-Lipkowska, M. Bryszewska, D. Shcharbin, M. Labieniec, Biological properties of low molecular mass peptide dendrimers // International Journal of Pharmaceutics. 2006, 309 (1-2), 208-217. Impact Factor = 3.61. http://preview.ncbi.nlm.nih.gov/pubmed/16930888

5. Klajnert B., W. Walach, M. Bryszewska, A. Dworak, D. Shcharbin. Cytotoxicity, haematotoxicity and genotoxicity of high molecular arborescent polyoxyethylene with polyglycidol block containing shell // Cell Biology International. 2006, 30 (3), 248-252. Impact Factor = 1.75. http://preview.ncbi.nlm.nih.gov/pubmed/16378736

6. Shcharbin D., M. Jokiel, B. Klajnert, M. Bryszewska. Effect of dendrimers on pure acetylcholinesterase activity and structure // Bioelectrochemistry. 2006, 68 (1), 56-59. Impact Factor = 3.52. http://preview.ncbi.nlm.nih.gov/pubmed/15923153

2005

1. Shcharbin D., B. Klajnert, V. Mazhul, M. Bryszewska. Dendrimer interactions with hydrophobic fluorescent probes and human serum albumin // Journal of Fluorescence. 2005, 15 (1), 21-29. Impact Factor = 1.97. http://preview.ncbi.nlm.nih.gov/pubmed/15711873

2. Shcharbin D., B. Klajnert, M. Bryszewska. The Effect of PAMAM dendrimers on human and bovine serum albumins at different pH and NaCl salt concentrations // Journal of Biomaterial Science, Polymer Edn. 2005, 16 (9), 1081–1093. Impact Factor = 1.84. http://preview.ncbi.nlm.nih.gov/pubmed/16231600

3. D. Shcharbin, The impact of polyamidoamine dendrimers on bilirubin absorbance // Proceedings of the National Academy of Sciences of Belarus (Vestsi Natsiyanalnai Akademii Navuk Belarusi), 2005, Number 5, part 2. P. 113-115. (In Russian).

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ГЛАВЫ В КНИГАХ:

1. V. Dzmitruk, D. Shcharbin, E. Pedziwiatr, M. Bryszewska (2011). Dendrimers in Anti-HIV Therapy, p. 361-374. Chapter 16 in book: Advances in Nanocomposite Technology, Dr. Abbass Hashim (Ed.), InTech, 2012, Open access article. Available from: http://www.intechopen.com/books/advances-in-nanocomposite-technology/dendrimers-in-anti-hiv-therapy

2. V. A. Kulchitsky, M. V. Talabaev, A. N. Chernov, D. G. Grigoriev, Y. E. Demidchik, D. G. Shcharbin, N. M. Chekan, V. V. Kazbanov, T. A. Gurinovich, A. I. Gordienko, E. K. Sergeeva, V. I. Potkin, V. N. Kalunov (2011). Improving the Efficiency of Chemotherapeutic Drugs by the Action on Neuroepithelial Tumors, p. 465-486. Chapter 21 in book: Glioma - Exploring Its Biology and Practical Relevance, Dr. Anirban Ghosh (Ed.), InTech, 2012, Open access article. Available from: http://www.intechopen.com/books/glioma-exploring-its-biology-and-practical-relevance/improving-the-efficiency-of-chemotherapeutic-drugs-by-the-action-on-neuroepithelial-tumors

3. D. Shcharbin, V. Dzmitruk, I. Halets, E. Pedziwiatr-Werbicka, M. Bryszewska (2012), Dendrimers in biology and medicine, p. 126-139. Chapter 10 in book: Nanomedicine and Drug Delivery, book series: ‘Recent Advances in Nanoscience and Nanotechnology’, 2012, Volume 1. M. Sebastian, N. Ninan, A.K. Haghi (Eds.), Apple Academic Press: Toronto, New Jersey (USA), 2012. http://www.ncbi.nlm.nih.gov/nlmcatalog/101596223

4. R. Gómez, F. J. de la Mata, J. L. Jiménez‐Fuentes, P. Ortega, B. Klajnert, E. Pedziwiatr‐Werbicka, D. Shcharbin, M. Bryszewska, M. Maly, J. Maly, M.J. Serramía, R. Lorente and M. A. Muñoz‐Fernández (2013). Cationic Carbosilane Dendrimers as Non‐viral Vectors of Nucleic Acids (Oligonucleotide or siRNA) for Gene Therapy Purposes, p. 40-55. Chapter in Book: ‘Dendrimers in Biomedical Applications’, B. Klajnert, L. Peng, V. Cena (Eds.), RSC Publishing, London (UK), 2012. http://dx.doi.org/10.1039/9781849737296

5. A.J. Perisé-Barrios, D. Sepúlveda-Crespo, D. Shcharbin, B. Rasines, R. Gómez, B. Klajnert-Maculewicz, M. Bryszewska, F.J. De La Mata, M.A. Muñoz-Fernández (2014). Dendrimers. pp. 246-279. Chapter 7 in book “Soft Nanoparticles for Biomedical Applications”, Series: RSC Nanoscience & Nanotechnology (Eds: J. Callejas-Fernández, J. Estelrich, M. Quesada-Pérez, J. Forcada), 2014, Issue 34, ISBN: 978-1-84973-811-8, 410 p. http://pubs.rsc.org/en/content/chapter/bk9781849738118-00246/978-1-84973-811-8

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  • Протеомика: внутримолекулярная динамика и функциональная активность белков

  • Окислительный стресс и процессы перекисного окисления липидов в биологических системах

Результаты исследований по внутримолекулярной динамике и функциональной активности белков и окислительному стрессу в биологических системах опубликованы в 1 монографии, 1 учебном пособии, 3 разделах в коллективных монографиях и более чем в 300 публикациях.

КНИГИ:

1. Мажуль В. М. Межклеточные контакты. Минск: Наука и техника, 1977. 290 c. (Mazhul’ V.M. Intercellular contacts, Minsk: Nauka & Technika, 1977. 290 p. In Russian).

2. В.И. Крот, И.В. Галец, Т.В. Музыка, А.В. Мучковский, Н.А. Прокошина, Д.Г. Щербин. Лучевая катаракта. Метод. пособие к лаб. практ. для студ. физ. - Минск: БГУ, 2012. - 60 с.

ГЛАВЫ В КНИГАХ:

1. Vladimir M. Mazhul’, Alexander V. Timoshenko, Ekaterina M. Zaitseva, Svetlana G. Loznikova, Inessa V. Halets and Tatsiana S. Chernovets. Room Temperature Tryptophan Phosphorescence of Proteins in the Composition of Biological Membranes and Solutions // in Book: Reviews in Fluorescence, 2010, Volume 2008, 37-67, DOI: 10.1007/978-1-4419-1260-2_2 - Ch. 2. - P. 37–67. http://www.springerlink.com/content/ql871pv273364540/

2. V.M. Mazhul, E.M. Zaitseva, D.G. Shcharbin. Protein: Strategy of Functioning // Chapter 3 in book: Biophysics of Living Systems: from Molecule to Organism. I.V. Volotovski Ed. Minsk: BelSens. 2002. pp. 27-48 (In Russian).

3. V.M. Mazhul, D.G. Shcharbin. Phosphorescent Analysis of Lipid Peroxidation Products in vitro and in situ // Chapter 10 in book: Photobiology and Membrane Biophysics. Volotovski Ed. Minsk: TechnoPrint. 1999. pp. 175-194 (In Russian).

СТАТЬИ В НАУЧНЫХ ЖУРНАЛАХ:

2013

1. Nikolaj Borisevich, Svetlana Loznikova, Aleksandr Sukhodola, Inessa Halets, Maria Bryszewska, Dzmitry Shcharbin, Acidosis, Magnesium and Acetylsalicylic acid: Effects on Thrombin // Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2013, Vol. 104, Pp. 158-164. Impact Factor 2012 = 1.977. http://www.sciencedirect.com/science/article/pii/S138614251201147X

2. В. Мажуль, И. Галец, Д. Щербин, А. Чекина. Катаракта: обнаружение патологии на молекулярном уровне // Наука и инновации. 2013. № 2. С. 23-25.

2012

1. Борисевич Н.А., Лозникова С.Ж., Суходола А.А., Щербин Д.Г. Фосфоресценция тромбина // Доклады НАН Беларуси. 2012. Т. 56. №2. с.57-62.

2. Галец И.В., Кравченок А.Л., Щербин Д.Г. Исследование внутримолекулярной динамики белков цитоскелета эритроцита человека спектрина и актина // Молодежь в науке – 2011: прил. к журн. «Весці Нацыянальнай акадэміі навук Беларусі». В 5 ч. Ч 3. Серия биологических наук; серия медицинских наук / редкол. серии биол. наук: И.Д. Волотовский (гл. ред.), В.И. Парфенов [и др.]; редкол. серии мед. наук: А.Г. Мрочек (гл. ред.), И.В. Залуцкий [и др.] – Минск: Беларус. навука, 2012. – С. 35–40.

2011

1. Д.Г. Щербин, С.Ж. Лозникова, В.А. Кульчицкий. Исследование действия трипсина на внутримолекулярную динамику мембранных белков клеток ткани спинного мозга крыс // Весці HAH Беларусі, cер. біял. навук, 2011, № 2, C. 73-77.

2. Галец И.В., Кравченок А.Л., Щербин Д.Г. Исследование внутримолекулярной динамики белков цитоскелета эритроцита человека спектрина и актина // Сборник материалов Международной конференции молодых ученых «Молодежь в науке – 2011» (Минск, 25–29 апреля 2011 г.).

2010

1. Mazhul V. M, Shcharbin D. G., Halets I. V., Kisel M. А. The effect of phospholipase A2 on protein internal dynamics of isolated human erythrocyte membranes. Proceedings of the National Academy of Sciences of Belarus, (Vestsi Natsiyanalnai Akademii Navuk Belarusi), Number 4, 2010, pp. 66-70. http://nasb.gov.by/eng/publications/vestib/vbi10_4.php

2009

1. C. Watala, A. Drapeza, V. Loban, M. Asztemborska, D. Shcharbin. Effect of acetylsalicylic acid on the current-voltage characteristics of planar lipid membranes // Biophysical Chemistry. 2009. V. 142(1-3). P. 27-33. Impact Factor = 2.108. http://www.sciencedirect.com/science/article/pii/S0301462209000507

2. Mazhul V. M., Shcharbin D. G., Halets I. V., Charnavets T. S. Phosphorescence of indole and its derivatives in matrix of polyvinyl alcohol. Proceedings of the National Academy of Sciences of Belarus, (Vestsi Natsiyanalnai Akademii Navuk Belarusi), Number 3, 2009, pp. 50-54. http://nasb.gov.by/eng/publications/vestib/vbi09_4.php

3. V. M. Mazhul’, I. V. Halets and T. S. Charnavets, Room-temperature tryptophan phosphorescence of proteins of isolated human erythrocyte membranes, Journal of Applied Spectroscopy, 2009, Volume 76, Number 2, Pages 250-256, http://www.springerlink.com/content/n747274k3×33l567/

4. Mazhul V. M., Halets I. V., Charnavets T. S., Shcharbin D. G. The intramolecular dynamics and conformational state of concanavalin A under the action of detergents. Proceedings of the National Academy of Sciences of Belarus, (Vestsi Natsiyanalnai Akademii Navuk Belarusi), Number 3, 2009, p. 68--71. http://nasb.gov.by/eng/publications/vestib/vbi09_3.php

2008

1. V. M. Mazhul’ and I. V. Galets, Tryptophan phosphorescence study of the influence of detergents on the internal dynamics of human erythrocyte membrane proteins // Biophysics, 2008, Volume 53, Number 4, Pages 286-289, http://www.springerlink.com/content/q67vw76×67179216/

2007

1. Мажуль В.М. Протеомика – новая наука ХХI века (Краткий обзор) // Экология и животный мир. – 2007. – №2. – С. 63–68.

2. V. M. Mazhul, S. Zh. Kananovich, T. S. Serchenya and O. V. Sviridov, Luminescence analysis of the structure of human alpha-1-microglobulin // Biophysics, 2007, Volume 52, Number 3, Pages 268-276. http://www.springerlink.com/content/p06227936q1231q0/

3. Chernovets TS, Mazhul’ VN. [Mechanisms of the protease-induced aggregation of human platelets] // Biofizika. 2007, 52(4):674-80. http://preview.ncbi.nlm.nih.gov/pubmed/17907408

2006

1. V. M. Mazhul’ and I. V. Galets, Tryptophan phosphorescence study of the internal dynamics of human erythrocyte membrane proteins upon spectrin modification // Biophysics, 2006, Volume 51, Number 3, Pages 359-363. http://www.springerlink.com/content/f77377l557651027/

2. V. M. Mazhul’ and S. Zh. Kananovich, Effect of temperature on the internal dynamics and the conformational state of bacterial alkaline phosphatase // Biophysics, 2006, Volume 51, Number 3, Pages 364-369. http://www.springerlink.com/content/0280242583052635/

2005

1. Мажуль В.М. Развитие исследований в области протеомики в Республике Беларусь: фундаментальные и прикладные аспекты // Наука и инновации, 2005. №7 (29). С.42–51.

2. Mazhul’ VM, Zaĭtseva EM, Shavlovskiĭ MM, Povarova OI, Kuznetsova IM, Turoverov KK. [Room temperature phosphorescence of amorphous aggregates and amyloid fibrils resulting from protein misfolding]. // Tsitologiia. 2005;47(11):978-87. http://preview.ncbi.nlm.nih.gov/pubmed/16706200

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